Proton translocating ATPases: Issues in structure and function

Structure, Function, and Evolution of Proton-ATPases.

Proton-ATPases are among the most important primary ion pumps in nature. There are three classes of these enzymes which are distinguished by their structure, function, mechanism of action, and evolution. They function in ATP formation at the expense of a protonmotive force generated by oxidative and photosynthetic electron transports, maintaining a constant pH in the cytoplasm, and forming acid...

Conservation of structure in proton-translocating ATPases of Escherichia coli and mitochondria.

arriving at (c ,+c ,+P) in the absence of antimycin must represent the oxidation of a second equivalent of QH, by the cyt. cI which remained oxidized after the first cycle of the complex. This second electron transfer presumably also occurs via the FeS centre, so that effectively the ‘invisible’ electron on the FeS centre gets replaced and pushed over on to cyt. c, in a second turnover of the c...

Fluoride inhibition of proton-translocating ATPases of oral bacteria.

The ATPases of isolated membranes of lactic acid bacteria were found to be inhibited by fluoride in a complex manner. Among the enzymes tested, that of Streptococcus mutans GS-5 was the most sensitive to fluoride, and the initial rate of hydrolysis of ATP was reduced 50% by approximately 3 mM fluoride. The enzyme of Lactobacillus casei ATCC 4646 was the most resistant, and about 25 mM fluoride ...

Structure , Function , and Evolution of Proton - ATPases Received for publication

Proton-ATPases are among the most important prmary ion pumps in nature. There are three classes of these enzymes which are distinguished by their structure, function, mechanism of action, and evolution. They function in ATP formation at the expense of a protonmotive force generated by oxidative and photosynthetic electron transports, maintaining a constant pH in the cytoplasm, and forming acidi...

Structure and function of proton-translocating adenosine triphosphatase (F0F1): biochemical and molecular biological approaches.